Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, certain intestinal disease colitis. Tell your doctor immediately farmaci suprax if any of these rare but very serious side effects occur: severe stomach abdominal pain, persistent nausea vomiting, yellowing eyes skin, dark urine, unusual tiredness, new signs of infection. Several patients developed severe diarrhea and or documented pseudomembranous colitis, and few required hospitalization. Tell your doctor immediately if you develop: persistent diarrhea, abdominal or stomach pain cramping, or blood mucus in your stool. Normal dose and schedule may be employed in patients with creatinine clearances of 60 mL min or greater. Appropriate cultures and susceptibility studies should be performed to determine the causative organism and its susceptibility to however, therapy may be started while awaiting the results of these studies. As result, many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases, may be susceptible to cefixime.